June 28, 2022

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Long-Covid Neurology: ‘Brain Fog’ as in Alzheimer’s

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dictate the condition brain fog It appeared as one of the most debilitating symptoms of long covid h It affects thousands of people around the world, affecting the ability to work and in daily life. Now a group of Australian scientists fromLa Trobe University in Melbourne They come close to solving the mystery of the persistent state that can lead to memory loss, confusion, dizziness, and headaches, making it difficult to remember commonly used words. The results of the just-published study Nature CommunicationsAnd the It suggests that there may be subtle similarities between the effects of Covid-19 on the brain and Early stages of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. As part of the study, researchers led by Prof. Nick ReynoldsFromInstitute of Molecular Sciences The same university used computer algorithms to identify small pieces of proteins, called peptides, in the SARS-CoV-2 virus. Then they studied the peptides in the laboratory, noting that they formed pools, reflecting the amyloid plaques found in the brain in the early stages of neurodegenerative diseases. “Amyloid plaques are highly toxic to brain cells and we hypothesize that the protein aggregates SARS-CoV-2 It can lead to neurological symptoms in COVID-19 Usually described as brain fog,” Professor Reynolds writes. If confirmed in future studies, he believes drugs developed to fight Alzheimer’s and Parkinson’s disease could be adapted to treat the debilitating neurological symptoms of long-term Covid. If brain fog is caused by amyloid plaques, we can count. over 30 years of pharmacological research for neurodegenerative diseases that can now be re-examined in the context of Covid-19.”

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